Molecular biology

Molecular biology

The Molecular Biology section is divided into two areas: Molecular Microbiology and Molecular Genetics. It performs urgent, priority, and routine analyses. The section consists of three well-differentiated work zones:

Zone 1 (Receipt of samplesand extraction of nucleic acids).

Zone 2 (PCR Preparation).

Zone 3 (Amplification and detection).

  • - Molecular microbiology based diagnosis of different infection-causing microorganisms (bacteria, viruses, fungi, mycobacteria, parasites…)

    - Molecular Epidemiology by means of Rep-PCR: Clonal studies.

    - Molecular Laboratory for the detection of different bacterial resistance mechanisms ( AMPc, Carbapenemases, ß-lactamases...)

    - Bacterial Genotyping.

    - Reference Laboratory for the molecular diagnosis of Sexually Transmitted Diseases (STDs).

    - Reference Laboratory for the Human Immunodeficiency Virus (HIV-1).

    Studies : Viral load

    - Study of the Hepatitis virus :

    Hepatitis B: Viral load and genotype.

    Hepatitis C: Viral load, genotype and sub-type.

  • Study of the Hepatitis virus (Accredited):

    - Hepatitis B: Viral load and genotype.

    - Hepatitis C: Viral load, genotype and sub-type.


  • Reference Laboratory for the Human Immunodeficiency Virus (HIV-1).Studies:

    - Viral load (Accredited).

    - Test of resistance to antiretrovirals by massive sequencing.

    - Test HLA-B*5701.

Molecular Genetics
  • Genotype Factor II (G20210A) (Accredited).
  • Genotype Factor V Leiden (Arg506Gln)(Accredited).
  • Genetic study of α-thalassemia.
  • Genetic study of Hemochromatosis (mutations p.His63Asp / p.Cys282Tyr) (Accredited).
  • Genotype ApoE.
  • Genotype HLA-B27.
  • Genetic study of susceptibility alleles in celiac disease

    (genotype HLA-DQ2.5/DQ2.2/DQ8).