Molecular biology
The Molecular Biology section is divided into two areas: Molecular Microbiology and Molecular Genetics. It performs urgent, priority, and routine analyses. The section consists of three well-differentiated work zones:
Zone 1 (Receipt of samplesand extraction of nucleic acids). Zone 2 (PCR Preparation). Zone 3 (Amplification and detection).
- Molecular microbiology based diagnosis of different infection-causing microorganisms (bacteria, viruses, fungi, mycobacteria, parasites…)
- Molecular Epidemiology by means of Rep-PCR: Clonal studies.
- Molecular Laboratory for the detection of different bacterial resistance mechanisms ( AMPc, Carbapenemases, ß-lactamases...)
- Bacterial Genotyping.
- Reference Laboratory for the molecular diagnosis of Sexually Transmitted Diseases (STDs).
- Reference Laboratory for the Human Immunodeficiency Virus (HIV-1).
Studies : Viral load
- Study of the Hepatitis virus :
Hepatitis B: Viral load and genotype.
Hepatitis C: Viral load, genotype and sub-type.
- Study of the Hepatitis virus (Accredited):
- Hepatitis B: Viral load and genotype.
- Hepatitis C: Viral load, genotype and sub-type.
- Reference Laboratory for the Human Immunodeficiency Virus (HIV-1).Studies:
- Viral load (Accredited).
- Test of resistance to antiretrovirals by massive sequencing.
- Test HLA-B*5701.
- Genotype Factor II (G20210A) (Accredited).
- Genotype Factor V Leiden (Arg506Gln)(Accredited).
- Genetic study of α-thalassemia.
- Genetic study of Hemochromatosis (mutations p.His63Asp / p.Cys282Tyr) (Accredited).
- Genotype ApoE.
- Genotype HLA-B27.
- Genetic study of susceptibility alleles in celiac disease
(genotype HLA-DQ2.5/DQ2.2/DQ8).