We start the year 2025 with renewed energy, continuing with our activity of publishing the "Catlab Informa". These monthly newsletters collect test and activity updates and other news about what we do at Catlab.

There are 2 new readings of these newsletters available:

-February: Procalcitonin and sepsis in the critically ill patient (click here)

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to a bacterial infection. Each hour of delay in diagnosis, attributable to lack of recognition during patient admission, is associated with a 7% reduction in survival. Procalcitonin (PCT) has revolutionized the management of sepsis, allowing for more accurate diagnosis and more efficient antibiotic management. The determination of PCT helps us to predict bacterial infection, distinguishing it from viral infections and other inflammatory processes, and differentiating between localized and systemic bacterial infections.

-January: Multiple Myeloma Genetic Analysis (click here)

Multiple myeloma (MM) is a hematological cancer that affects the plasma cells of the bone marrow and detection of chromosomal alterations is essential for its diagnosis and prognosis. Genetic abnormalities include primary changes such as IGH gene rearrangements and secondary changes such as TP53 deletion, which influence survival and response to treatment. A key tool for identifying these alterations is the fluorescent in situ hybridization (FISH) technique, which allows the detection of specific chromosomal abnormalities in plasma cells. At Catlab we perform the MultiFISH technique that facilitates the analysis of the most relevant genetic alterations in one go, improving the diagnosis and personalization of the treatment.